Publications

RNA Sequencing for Transcript 5′-End Mapping in Mycobacteria.
Martini, M.C.; Sun, H.; and Shell, S.S. Methods Mol Biol. 2021;2314:513-531. doi:10.1007/978-1-0716-1460-0_22

MamA essentiality in Mycobacterium smegmatis is explained by the presence of an apparent cognate restriction endonuclease.
Randall, S.E.*; Martini, M.C.*; Zhou, Y; Joubran, S.R.; and Shell, S.S. BMC Res Notes. 2020;13(1):462. doi:10.1186/s13104-020-05302-z
*Joint first authors.

Regulation of mRNA Stability During Bacterial Stress Responses.
Vargas-Blanco, D.A. and Shell, S.S. Front Microbiol. 2020;11:2111. doi:10.3389/fmicb.2020.02111

Artemisia annua and Artemisia afra extracts exhibit strong bactericidal activity against Mycobacterium tuberculosis.
Martini, C.M.; Zhang, T.; Williams, J.T.; Abramovitch, R.B.; Weathers, P.J.; and Shell, S.S. J Ethnopharmacol. 2020;262:113191. doi:10.1016/j.jep.2020.113191

The Impact of Leadered and Leaderless Gene Structures on Translation Efficiency, Transcript Stability, and Predicted Transcription Rates in Mycobacterium smegmatis.
Nguyen, T.A.*; Vargas-Blanco, D.A.*; Roberts, L.A.; and Shell, S.S. J Bacteriol. 2020;202(9):e00746-19. doi:10.1128/JB.00746-19
*Joint first authors.

mRNA Degradation Rates Are Coupled to Metabolic Status in Mycobacterium smegmatis.
Vargas-Blanco, D.A., Zhou, Y., Zamalloa, L.G., Antonelli, T., and Shell, S.S. mBio. 2019;10(4):e00957-19. doi:10.1128/mBio.00957-19

Defining the Transcriptional and Post-transcriptional Landscapes of Mycobacterium smegmatis in Aerobic Growth and Hypoxia.
Martini, C.M., Zhou, Y., Sun, H., and Shell, S.S. Front Microbiol. 2019;10:591. doi:10.3389/fmicb.2019.00591

Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. Journal of Immunology.
Keegan, C., Krutzik, S., Schenk, M., Scumpia, P.O., Lu, J., Pang, Y.L.J., Russell, B.S., Lim, K.S., Shell, S.S., Prestwich, E.G., Su, D., Elashoff, D., Hershberg, R.M., Bloom, B.R., Belisle, J.T., Fortune, S.M., Dedon, P.C., Pellegrini, M., Modlin, R.L. J Immunol. 2018;200(9):3244-3258. doi:10.4049/jimmunol.1701733

Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.
Shell, S.S.*, Wang, J.*, Lapierre, P., Mir, M., Chase, M.R., Pyle, M.M., Gawande, R., Ahmad, R., Sarracino, D.A., Ioerger, T.R., Fortune, S.M., Derbyshire, K.M., Wade, J.T. and Gray, T.A. PLoS Genet. 2015;11(11):e1005641. doi:10.1371/journal.pgen.1005641
*Joint first authors.

The Psp system of Mycobacterium tuberculosis integrates envelope stress sensing and envelope preserving functions.
Datta, P., Ravi, J., Guerrini, V., Chauhan, R., Neiditch, M.B., Shell, S.S., Fortune, S.M., Hancioglu, B., Igoshin, O., Gennaro, M.L. Mol Microbiol. 2015;97(3):408-422. doi:10.1111/mmi.13037

RNA sequencing for transcript 5′-end mapping in mycobacteria.
Shell, S.S., Chase, M.R., Ioerger, T.R., & Fortune, S.M. Methods Mol Biol. 2015;1285:31-45. doi:10.1007/978-1-4939-2450-9_3

DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis.
Shell, S.S., Prestwich, E.G., Baek, S.H., Shah, R.R., Sassetti, C.M., Dedon, P.C., and Fortune, S.M. PLoS Pathog. 2013;9(7):e1003419. doi:10.1371/journal.ppat.1003419

Interaction between the MSH2 and MSH6 nucleotide-binding sites in the S. cerevisiae MSH2-MSH6 complex.
Hargreaves, V.V., Shell, S.S., Mazur, D.J., Hess, M.T., and Kolodner, R.D. J Biol Chem. 2010;285(12):9301-9310. doi:10.1074/jbc.M109.096388

Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins.
Shell, S.S., Putnam, C.D., and Kolodner, R.D. Proc Natl Acad Sci U S A. 2007;104(26):10956-10961. doi:10.1073/pnas.0704148104

The N-terminal region of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA.
Shell, S.S.*, Putnam, C.D.*, and Kolodner, R.D. Mol Cell. 2007;26(4):565-578. doi:10.1016/j.molcel.2007.04.024
*Joint first authors.

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility.
Yang, G., Scherer, S.J., Shell, S.S., Yang., K., Kim, L., Lipkin, M., Kucherlapati, R., Kolodner, R.D., and Edelmann, W. Cancer Cell. 2004;6(2):139-150. doi:10.1016/j.ccr.2004.06.024