Lab News

April 2024: Congratulations to Huaming Sun for successfully defending his PhD dissertation! This significant milestone marks the culmination of years of hard work, dedication, and passion for his research.

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April 2024: Alana and Maddie presented their work at the undergraduate research project showcase. Great job! We’re so proud of you!!

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February 2024: Abby and Julia enjoyed their time at the annual Graduate Research Innovation Exchange (GRIE) at WPI along with their beautiful posters as usual!

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December 2023: Undergraduate students of BB3527 Molecular Biology and Genetic Engineering present their posters about how gene architecture affects translation efficiency in M. smegmatis.

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October 2023: Our paper on the impact of RNase E on mRNA degradation in mycobacteria is published. This project represents a long-term collaborative effort by a remarkable group of scientists. Congratulations to co-first authors Ying Zhou (PhD graduate) and Huaming Sun (current PhD student), also the rest of the team! Check it out here.

October 2023: Huaming presented his poster at Nature Conference – Cracking the Code: The Dawn of Nucleic Acid Medicines. Great to see our lab alumni Diego!

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October 2023: Congratulations to Vanesa for passing her qualifying exam and becoming a PhD Candidate!

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Sep 2023: Congratulations to lab alumni Sarah for starting her PhD journey in Biology at Boston College!

Sep 2023: Annual summer lab party with lab members and alums!

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August 2023: Our paper on the roles of sRNA B11 in M. abscessus is published. This project is collaborated with the lab of Daniel Barkan at The Hebrew University of Jerusalem. Congratulations to co-first authors Carla Martini (former postdoc) and Natalia Alonso (former postdoc), also the rest of the team! Check it out here.

June 2023: Annual fun meeting with groups of amazing scientists! Shell lab at the Boston Bacterial Meeting.

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June 2023: Julia presented her poster at the Boston Bacterial Meeting leaving everyone minds swirling with inspiration.

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June 2023: Julia represented WPI office of graduate studies at BIO International Convention 2023.

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May 2023: Shell lab at Pathway Analysis in TB meeting at Weill Cornell Medical College.

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April 2023: Livvie presented her senior project. Great job Livvie!

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April 2023: Abby passed her qualifying exam! Congratulations candidate Abby!!

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March 2023: Shell lab at the Pioneer Valley Microbiology Symposium! Julia wowed the crowed once again with her gorgeous poster.

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Februry 2023: Julia presented her gorgeous poster at WPI graduate student recruitment event.

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February 2023: Can’t believe it’s almost been two years since our terrific postdoc Natalia Alonso joined the lab. We got together to celebrate her wonderful time with us. We wish Nati all the best with her new adventures in Argentina!

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February 2023: Our paper on the effects of Artemisia annua and Artemisia afra extracts on bactericidal activity against Mtb is published. This project is a continuous collaboration with the lab of Pam Weathers at WPI. Congratulations to co-first author Natalia Alonso! Check it out here.

January 2023: Our paper on undergraduate research experience in an upper-level molecular biology laboratory course is published. This project is collaborated with Prof. Lou Roberts at WPI. Congratulations to Lou and Scarlet! Check it out here.

December 2022: Undergraduate students of BB3527 Molecular Biology and Genetic Engineering present their posters about using an ATc-inducible CRISPRi approach to knock down expression of PNPase or RNase E in strains harboring deletions of khpB, rnj, helY, rhlE1, or rhlE2 in M. smegmatis.

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October 2022: TB lab family reunion with Rubin, Fortune, Sassetti, Ehrt, Rock, Schnappinger and Rhee labs at Connecticut.

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September 2022: Lab celebrating Sarah’s new adventure at Brigham and Women’s Hospital. We’ll miss you, Sarah!!

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August 2022: Rebecca and Liz present their awesome summer research at WPI Research Experiences for Teachers (RET) poster session.

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August 2022: Our fantastic undergrads, Maddie, Alana and Daniel, showing off their summer research project.

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July 2022: Summer lab party!!

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July 2022: Our paper on the roles of RNase J in mycobacterial RNA metabolism is published. This project is collaborated with the lab of Sarah Fortune at Harvard T.H. Chan School of Public Health. Congratulations to co-first author Carla Martini (former postdoc) and the rest of the team! Check it out here.

July 2022: Huaming presents his research at ISMB 2022 Madison.

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June 2022: We’re having so much fun at Boston Bacterial Meeting!! Huaming gets the best graduate student poster prize.

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May 2022: Welcome to Vanesa Lopa and Opeyemi Ibitoye, our newest PhD students!

May 2022: Welcome to our newest undergrad, REU students Eva Plankey and Alana Lue Chee Lip!

May 2022: Congratulations to Catherine Masiello, Adrian Orszulak, and Van Le who completed their senior projects in the Shell lab and were awarded their BS degrees. Adrian is going to be a PhD student in Biomedical Sciences at UMass Chan Medical School, Catherine will be working as a Research Associate II for the Metagenomics Discovery Team at Arbor Biotechnologies, and Van will be Research Associate of Preclinical Biomarkers at Caraway Therapeutics.

May 2022: Congratulations to Catherine Masiello for receiving BBT Department 2nd Place MQP Award!

April 2022: Catherine Masiello, Adrian Orszulak, and Van Le present their senior projects.

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May 2022: Undergraduate students of BB3527 Molecular Biology and Genetic Engineering present their posters about using an ATc-inducible CRISPRi approach to knock down expression of key proteins in RNA metabolism in M. smegmatis.

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April 2022: Julia and Huaming present at the WPI’s Graduate Research and Innovation Exchange finals!

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March 2022: Congratulations to Huaming for passing his qualifying exam and becoming a PhD Candidate!

March 2022: Shell lab at Northeast World Tuberculosis Day Conference at Tufts University.

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March 2022: We’re finally out for a conference in person at the Pioneer Valley Microbiology Symposium!!! Huaming gives a talk.

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January 2022: Welcome to Vanesa Lopa and Opeyemi Ibitoye, our new rotation students!

December 2021: Welcome to Abby Rapiejko, our newest PhD student!

December 2021: Welcome to Hilario Cafiero, our new postdoc!

October 2021: Congratulations to Julia for passing her qualifying exam and becoming a PhD Candidate!

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October 2021: We say a bittersweet goodbye to Carla Martini, who is off to a faculty-track position in Argentina. We will miss Carla tremendously but we are so happy to see her taking the next big step in her career!

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September 2021: Welcome to our new NSF-funded post-baccalaureate student, Sarah Bibeau!

September 2021: Welcome to new rotation students Edward Chocano Coralla and Danielle Costello!

July 2021: Shell lab members and recent lab alums gather to celebrate a host of 2020-2021 accomplishments including papers published, grants awarded, MQPs completed, babies born, and Scarlet’s tenure!

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July 2021: Welcome to Sarah Shepro, Worcester high school teacher in residence in the Shell lab for the summer  (NSF RET award).

June 2021: The Shell lab and collaborators are awarded an NIH grant to study the roles of small RNAs in gene regulation and virulence of mycobateria (NIAID 1 R21 AI156415-01A1).

June 2021: Welcome to our newest undergrad, REU student Hannah Allen!

June 2021: PhD students Huaming Sun and Ying Zhou present posters at the Boston Bacterial Meeting.

May 2021: Congratulations to Jessica Kelly for winning the Provost’s MQP award for Bioinformatics and Computational Biology!

May 2021: Congratulations to Ryan Peters for receiving the third place Biology and Biotechnology Poster Presentation Day award!

May 2021: Congratulations to Jessica Kelly, Samantha Joubran, and Ryan Peters who completed their senior projects in the Shell lab and were awarded their BS degrees. Samantha and Ryan are off to grad school in the fall (Harvard University Chemical Biology PhD program and Purdue University Biological Sciences PhD program, respectively), and Jess is a research assistant in the Friedman lab at Beth Israel Deaconess Medical Center.

May 2021: Under the direction of Prof. Lou Roberts, undergraduates in lab course BB3527 begin investigating the gene products that modify mRNA 5′ ends in mycobacteria.

May 2021: The Shell lab gathers in person for the first time in over a year for a picnic party to celebrate Diego’s graduation.

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May 2021: Welcome to new postdoc Natalia Alonso! Natalia received her PhD at the University of Buenos Aires, Argentina, and then worked as an Assistant Research Scientist at the Institute of Agrobiotechnology and Molecular Biology in Buenos Aires.

February 2021: Welcome to BCB PhD rotation student Junpei Xiao and new undergrad volunteers Livvie Atkins, Amelia Sadlon, and Daniel Larrabee!

December 2020: Congratulations to Diego Vargas Blanco for successfully defending his PhD dissertation!

September 2020: The Shell lab and a team of collaborators are awarded an NIH grant to study the mechanisms of antimycobacterial activity by Artemisia plant extracts (NIAID 1 R21 AI151481-01).

September 2020: Our paper on the role of the DNA methyltransferase MamA is published. This paper is the culmination of work by two WPI undergrads as well as PhD student Ying Zhou and postdoc Carla Martini. Congratulations to the team! You can find it here.

September 2020: Our paper on Regulation of mRNA Stability During Bacterial Stress Responses is published. Congratulations to Diego Vargas-Blanco and Scarlet Shell! You can find it here.

August 2020: Undergrads Catherine Masiello, Justin Moy, Jessica Kelly, and Adrian Orszulak complete summer bioinformatics projects – the science goes on, in spite of covid!

July 2020: The Shell lab together with a team of collaborators across the country are awarded an NIH program project grant to study pathways required for stress tolerance and antibiotic tolerance in Mycobacterium tuberculosis (NIAID 1 P01 AI143575-01A1).

July 2020: Congratulations to Carla Martini (postdoc) on the birth of her new baby, Lucas!

July 2020: Our paper on the antimycobacterial properties of Artemisia plant extracts is published. This project is an exciting new collaboration with the lab of Pam Weathers at WPI. Congratulations to first author Carla Martini (postdoc) and the rest of the team! Check it out here.

June 2020: Grad students and postdoc are back in the lab and dancing joyfully from the freezer to the RNA bench!

June 2020: Congratulations to Shell lab alum Alexa Davis (B.S., 2020) on her new position as a research associate at Abcam Life Sciences!

June 2020: Congratulations to Shell lab alum Joe Dainis (B.S., 2020) on his new position as a research technician at Brown University!

April 2020: More exciting news in April. Scarlet was awarded the WPI Sigma Xi Outstanding Junior Faculty Research Award! Congratulations!

April 2020: Congratulations to Karina Franca (B.S., 2020)! Karina will be attending the Boston University School of Medicine for a Masters of Science in Genetic Counseling Program starting Fall 2020.

April 2020: Our newest paper is out and it is our first paper to have an undergraduate as co-first author. Congratulations Tien Nguyen (B.S.) and Diego Vargas-Blanco (Ph.D. candidate). Check it out.

April 2020: While our weekly meetings changed format, we are still eager to do science and share our findings… though we can’t help but feel nostalgic about the RNA bench.

Feb 2020: Ying, Diego and Huaming at the WPI’s Graduate Research and Innovation Exchange poster celebration day. Ying and Diego made it to the finals!

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Nov 2019: lab game night!

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Fall 2019: welcome to Julia, our newest PhD student!

Summer 2019: recent WPI grads Sam and Tien get exciting jobs as research technicians.

July 2019: Scarlet is elected to chair the Gordon Research Conference on Mechanisms of Microbial Transcription in 2023.

July 2019: Diego is elected to chair the Gordon Research Seminar on Tuberculosis Drug Development in 2021.

June 2019: Lunch to celebrate Diego’s mBio paper.

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June 2019: Sam gives a lightening talk at the Boston Bacterial Meeting and wins the prize for best undergraduate poster.

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May 2019: Three fantastic students – Oscar, Tien, and Sam – receive their Bachelor’s degrees.

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May 2019: Sam, Tien, and Oscar present their senior projects.

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May 2019: Celebrating Scarlet’s WPI Board of Trustees Award for Outstanding Academic Advising.

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April 2019: Diego wins best life sciences poster the the WPI Graduate Research and Innovation Exchange, and Sam wins the Salisbury prize for excellence in Biology and Biotechnology (with WPI president Laurie Leshin and WPI provost Wole Soboyejo).

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April 2019: WPI undergrads contribute to the Shell lab’s research mission in a course-based research experience (with Associate Teaching Professor Lou Roberts).

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April 2019: lab game night!

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March 8, 2019: Carla’s paper is accepted for publication by Frontiers in Microbiology. Time for a celebration lunch!

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March 7, 2019: Diego presents his work at the Boston TB Meeting

February 6, 2019: Diego and Huaming present their work at WPI’s Graduate Research and Innovation Exchange

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January 2019: Ying gives a talk at the Pioneer Valley Microbiology Symposium

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January 2019: Scarlet gives a talk and Carla presents a poster at Keystone Tuberculosis in Banff, Alberta

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